Registries vary widely in geographic scope. Some registries collect data at a local or regional level, while others collect data at a national or multinational level. Multinational registries, also called multicountry, global, or international registries, offer unique research opportunities beyond those offered by national, regional, or local registries. By collecting data from multiple countries, these registries are able to examine geographic variations in disease etiology and progression as well as treatment patterns and clinical effectiveness in various populations.
Multinational registries also may be able to enroll larger numbers of patients, which can enhance their capacity to detect adverse events, should they exist, and to better understand rare conditions.