To encourage consistency in analytic approaches when modeling, ICER has defined a “reference case” specifying the approach that ICER and its collaborators follow for cost-effectiveness analyses.
The reference case is defined by the components, methods, and reporting elements to be used in a cost-effectiveness analysis. ICER’s reference case generally aligns with the Second Panel on Cost-Effectiveness in Health and Medicine’s recommendations for a health care perspective reference case. Note that following the reference case does not preclude additional analyses being conducted, and reasons may exist for deviating from the reference case to reflect particular circumstances.
In these cases, any deviations from the reference case will be clearly specified and justified in the model analysis plan and Evidence Report.
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