Traditional real-world evidence (RWE) is based on data collected in normal clinical practice outside of randomized controlled trials. It is used to complement clinical data in regulatory and health technology assessment submissions. This data is most often generated through retrospective or prospective observational studies using electronic health records, medical claims, disease registries, etc. As more emphasis is placed on the importance of RWE, other sources of useful real-world data have been identified, specifically social media. Online technology platforms have allowed patients to interact with each other and provide unique insight into specific diseases, conditions, and treatments. Mining this health-related social media data provides invaluable real-world data.
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