Associate Director, Health Economics & Outcomes Research

Agios Pharmaceuticals
November 6, 2018
Cambridge, Massachusetts
Job Type
Job Level
Associate Director


Agios ( is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has two approved oncology precision medicines and multiple first-in-class investigational therapies in clinical and/or preclinical development.

The Associate Director of HEOR will help drive health economics and outcomes research activities in support of products in the rare genetic disease (RGD) and hematology/oncology portfolio. The Associate Director of HEOR will be responsible for demonstrating the clinical, economic, and humanistic value of Agios’s products and developing deliverables that communicate this value to external stakeholders, including payers, patients, providers, and other healthcare decision makers. He/she will be accountable for designing and executing research that is medically relevant, scientifically valid, and aligned with the evidence generation needs across the portfolio. This role will report to the Senior Director of Health Economics & Outcomes Research and be based in Cambridge, MA.

Responsibilities Will Include, But Are Not Limited To, The Following

  • Develop HEOR strategic approaches for products in different stages of development, while maintaining in-depth knowledge of the disease state , medical practice standards, market & customer dynamics, the competitive landscape, and reimbursement issues
  • Work closely with Clinical Development, Medical Affairs, Commercial, and Market Access teams to understand the HEOR needs of the business
  • Provide HEOR functional expertise on cross-functional strategy teams
  • Design, implement, and manage health economics and outcomes research projects, including but not limited to quality of life studies, retrospective database analyses, economic models, chart reviews, qualitative research, and systematic literature reviews
  • Work with clinical development teams to identify appropriate patient-reported and related outcome measures for inclusion in clinical trials and Agios-sponsored registries
  • Translate output from HEOR initiatives into tools and resources for field teams
  • Develop product value messages and work with colleagues across the organization to educate on the value proposition of the company’s products to internal and external stakeholders
  • Prepare global value and reimbursement dossiers
  • Present health economics and outcomes research findings at scientific congresses and participate in the development and writing of manuscripts for publication in peer-reviewed journals
  • Manage relationships and budgets with vendors to ensure timely completion of high quality, customer-relevant projects
  • Build strong relationships with internal stakeholders and ensure continuous and consistent communication with key internal partners on HEOR projects
  • Ensure compliance with all applicable laws, AGIOS policies, regulations and regulatory guidelines governing commercial and scientific interactions with healthcare professionals, payers, advocacy and other business partners.

Required Knowledge, Skills, and Abilities

  • Master’s or doctoral degree in health economics, epidemiology, health services research, public health, or related field
  • HEOR experience within the pharmaceutical/biotechnology industry: minimum 3 years with a doctoral degree or 5 years with a master’s degree
  • Demonstrated technical and strategic excellence in designing, conducting, and interpreting health economics and outcomes research, with a particular emphasis on quality of life and other patient-reported outcomes assessments
  • Experience working in rare diseases
  • Excellent written and verbal communication skills,
  • Strong interpersonal skills and ability to collaborate on cross-functional teams
  • Ability to navigate ambiguous, complex, and difficult situations
  • Ability to interface with multiple stakeholders, including clinicians and payers
  • Solid understanding of US healthcare delivery systems and reimbursement processes for pharmaceuticals in the U.S. and major international markets
  • Strong project management skills
  • Ability to travel approximately 10-15% of the time
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