Is Real-World Evidence Used in P&T Monographs and Therapeutic Class Reviews?

Little is known about when and what types of real-world evidence (RWE) studies inform pharmacy and therapeutic (P&T) committee decisions. To address this gap in knowledge, researchers evaluated evidence sources cited in P&T committee monographs and therapeutic class reviews and assessed the design features and quality of cited RWE studies.

They found that RWE was infrequently cited in P&T materials, even among therapeutic class reviews where RWE is more readily available. Although few P&T materials cited RWE, the comparative RWE studies were generally high quality. More research is needed to understand when and what types of real-world studies can more routinely inform coverage and reimbursement decisions. Read the full study here.

(Source: Is Real-World Evidence Used in P&T Monographs and Therapeutic Class Reviews? Jason T. Hurwitz, Mary Brown, Jennifer S. Graff, Loretta Peters, and Daniel C. Malone Journal of Managed Care & Specialty Pharmacy 2020 26:12, 1604-1611)