Cytel Paper on De-Risking Clinical Trials Using a Data-Driven Method

Cytel has published a position paper on using data to de-risk clinical trials. The paper discusses methods that can be used to determine the pros and cons of several study designs and how to rapidly accelerate an ongoing trial without compromising its power. The whitepaper offers clear strategies to improve your decision-making in clinical trial design.

“For many decades the Pareto Frontier has been employed by actors in the private sector to evaluate and understand the benefits of various strategic options. When trying to understand the risks and benefits of a clinical strategy, Cytel researchers urge using a modified version of this process, built primarily with clinical development in mind. Their new position paper describes two functional uses of the Pareto concept for clinical trials – the selection of a de-risked trial design, and an improved understanding of the financial nature of the tradeoffs between various operational parameters of clinical trial design.” Read more here.

(Source: Esha Senchaudhuri, Cytel, 6/2/21)