Observational studies can make for a suitable alternative for randomized trials when facing financial or other constraints, and a recent article offers some considerations to help reduce the risk of bias in the most common observational study design: the cohort study.
The article by The Department of Primary Care and Population Health’s Manuj Sharma et al. spotlights some key issues that should be addressed while the question is under development and while the study is being designed.
“A comparison of outcomes across treated and untreated individuals in an observational study may lead one to erroneously conclude that treatment is not effective, when in fact the treatment may have been selectively given to those with the worst prognosis,” the article states.
To read the full article, click here.