The ubiquitous adoption of electronic health records (EHR) has supported the explosion of real-world data (RWD) applications in clinical trials. RWD has the potential to accelerate and optimize clinical trials while expanding their reach. In a new Life Science Leader article, learn more about the many ways that RWD can improve clinical trials and accelerate clinical development and market access.
According to Ellen Loo, “Researchers can use RWD to optimize study design, so the study can generate statistically significant, unbiased results with fewer subjects. With a more comprehensive data set provided through RWD for each patient, researchers are able to apply advanced statistical methods to match cases more effectively to controls. These methods can identify certain factors in a control patient that suggest greater propensity for developing particular conditions that mirror a case. For example, a patient undergoing a diagnostic workup for cirrhosis may have a greater propensity for developing liver cancer. Employing these insights in case-control matching reduces bias from confounding variables as well as the number of patients needed for a study.”
To read more, click here.
(Source: Life Science Leader, May 10th, 2023)